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Bei Sha Shen - Glehnia littoralis
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Professional Data |
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Pin Yin
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Bei Sha Shen
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Latin
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Radix Glehniae
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Introduction |
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Radix glehniae is the dried root of Glehnia littoralis Fr. Schmidt ex Miq. (Fam. Umbelliferae). The drug is collected in summer and autumn, removed from rootlet, washed clean, dried slightly in the air, treated with boiling water, peeled and dried, or dried immediately directly after washing.
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Western medical |
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The herb is indicated in the treatment of pneumonia, mouth ulcer, hoarse voice, esophagitis, etc..
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Eastern medical |
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- Pattern: Nourishes yin, clears the Lung, benefits the Stomach and generates Fluid.
- Properties: Sweet, slightly bitter, slightly cold.
- Channels entered: Lung and Stomach.
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Chemical constituents |
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The herb contains alkaloids, starch and polysaccharide, etc..
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Pharmacological actions |
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Anti-febrile and analgesic effects |
Ethanol extract of the root could slightly lower the body onload="highlight();" temperature of normal rabbits, it could also lower the temperature of rabbits with fever induced by typhoid vaccine. Besides, it had analgesic effect on pain reaction caused by electric stimulation on dental pulp of rabbits. |
Effects on cardiovascular system |
Water immersion at low concentration could strengthen the contraction of isolated toad's heart; with the increasing of concentration, it showed inhibitory effect till the ventricle stopped beating (meanwhile the artrium may still beat) which could be restored. It had similar effects on in vivo toad's heart. Intravenous injection to anaesthetized rabbits could slightly increase the blood pressure and strengthen the respiration. |
Others |
Polysaccharide of bei sha shen had immunosuppressive activity.
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Clinical Studies |
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Infantile persistent pneumonia |
bei sha shen and shan yao, 15g each were decocted to treat 24 cases of infantile persistent pneumonia whose courses varied from 1 to 3 months. Results: In 12 cases, main symptoms and signs disappeared and had no recurrence; in 9 cases, symptoms and signs disappeared; and 3 cases were ineffective. |
Esophagitis |
sha shen, mai dong, gan cao, jie geng, jin yin hua, lian qiao 100g each and pang da hai 50g were made into honey pills, 1~2 pills, 3~5 times daily. 12 cases were treated, 8 were cured, 3 improved and 1 ineffective. |
Infantile oral ulcer |
Sha Shen Mai Dong Tang (sha shen, mai dong, yu zhu, tian hua fen, bian dou, 6~9g each; dong sang ye 6g; gan cao 3~6g; da qing ye, ren zhong bai, 9~12g), water decoction, 1 dose every day. 34 cases of infantile mouth ulcer were treated and all were cured. The ulcer usually healed after 2~5 doses, averagely 2 doses. |
Hoarse voice |
sha shen, shi gao 15g, gan cao 9g, xing ren, mi zhi pi pa ye, 10g each; e jiao, mai dong, hei zhi ma, dong sang ye, mu hu die, 12g each. Modify the formula according to accompanied symptoms. 85 cases of hoarseness were treated, and all were cured except one effective. |
Toothache caused by deficient Fire |
bei sha shen, di gu pi, 15g each; sheng di, zhi mu, 9g each; xi xin 1.5g, water decoction. The method had significant effect on toothache caused by deficient Fire. |
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References |
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Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998 |
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