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Bing Lang - Areca catechu
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Professional Data |
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Pin Yin
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Bing Lang
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Latin
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Semen Arecae
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Introduction |
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Semen Arecae is the dried ripe seed of Areca catechu L. (Fam. Palmae). The ripe fruit is collected from late spring to early autumn, boiled in water dried, removed from pericarp, and the seed is collected, then dried.
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Western medical |
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The herb is used to treat chylous urine due to filariasis, bacillary dysentery, biliary ascariasis, cestodiasis and acute necrotic enteritis, etc..
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Eastern medical |
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- Pattern: Kills parasites, eliminates stagnated food, lowers qi, promotes water circulation and treats malaria.
- Properties: Bitter, pungent, warm.
- Channels entered: Stomach and Large Intestine.
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Chemical constituents |
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The drug contains alkaloids, condensed tannin, fat, areca red. Arecoline is the main alkaloid in bing lang.
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Pharmacological actions |
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Helminthic effect |
Arecoline is the effective ingredient of bing lang's helminthic effect. It could paralyze the whole body onload="highlight();" of pork tapeworm. It could only paralyze the cephalomere and immature proglottis of taenia saginata. In vitro tests showed that it also had paralyzing effect on threadworm. It could poison ascaris. |
Anti-fungi and anti-viral effects |
1:1 water immersion of bing lang had inhibitory effect on some dermatomyces to different degrees. The anti-viral effect of bing lang was related to its tannin. Its decoction and water immersion had inhibitory effect on some strains of influenza type A virus. |
Effects on cholinergic receptor |
Arecoline had similar effects to pilocarpine. It could excite M-cholinergic receptor., led to the increase of gland secretions, contractions of bronchia, decrease of heart rate, dilation of blood vessel and lowering blood pressure. Used as eye drop, it could decrease the pupils. It could also increase the intestinal peristalsis. |
Anticancer effect |
Polyphenolic substance obtained from bing lang had obvious inhibitory effect on Ehrlich carcinoma, it had medium cytoxic effect on Hela cells. |
Anti-cell adhesion |
Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: screening of 232 herbal drugs for anti-cell adhesion. |
Among 232 herbal drugs tested, six showed a remarkable anti-cell adhesive activity, and the extract from the roots of Bupleurum falcatum (Umbelliferae), the semen of Psorala corylifolia (Leguminosae), and the semen of Areca catechu (Palmae) showed an anti-cell adhesive action at non-cytotoxic concentrations. Saikosaponins-a, d and e, isolated from the roots of Bupleurum falcatum, exhibited a potent anti-cell adhesive activity and a strong hemolytic action. In a structure-activity relationship for both activities, it seems that a sugar moiety and an ether linkage between C-13 and C-28 are required for good bioactivities. In addition, saikosaponin d with a beta-hydroxy group at C-16 was more potent than saikosaponin a possessing an alpha-hydroxy group. Taken together, it is suggested that the mechanism for anti-cell adhesive activity of saikosaponin may resemble that for their hemolytic action. |
--Ahn BZ, Yoon YD, Lee YH, Kim BH, Sok DE. Planta Med. 1998 Apr;64(3):220-4.
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Clinical Studies |
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Chylous urine due to filariasis |
ku shen 20g; bing lang, di long, bi xie, hai zao, 10g each; shan zha, 30g; fu ling, che qian zi, 15g each; water decoction. The preparation may be changed to honeyed pill after symptoms disappeared. |
Bacillary dysentery |
wu mei, ai ye, bing lang, chuan jiao, chi shi zhi, gan jiang, huang qin, huang lian. Water decoction. |
Cestodiasis |
Fresh shan zha 1kg, bing lang 60g. No supper except shan zha. Take bing lang decoction on the second morning. |
Biliary ascariasis |
yin chen, wu mei, zhi ke, mang xiao, 9g each; bai shao, chuan jiao, 4.5g, bing lang 12g, da huang 6g, water decoction, 1~3 days. |
Acute necrotic enteritis |
da huang, lian qiao, 10~15g; zhi shi, tao ren, hong hua, mu xiang, bing lang, 5~10g; chi shao, 10g; jin yin hua 15~30g, water decoction. |
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References |
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Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998 |
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