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Jiang Huang - Curcuma longa
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Professional Data |
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 Pin Yin
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Jiang Huang
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| Latin
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Rhizoma Curcumae longae
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| Introduction |
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Rhizoma Curcumae longae is the dried rhizome of Curcuma longa L. (Fam. Zingiberaceae). The drug is collected in winter when the aerial part wither, washed clean, boiled or steamed thoroughly, dried in the sun and removed from fibrous root.
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| Western medical |
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jiang huang is indicated in the treatment of hyperlipema, stye and otitis media, etc..
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| Eastern medical |
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- Pattern: Activates Blood, dissolves stagnanted Blood, moves qi, alleviates pain, promotes menstruation and relieves edema.
- Properties: Pungent, bitter, warm.
- Channels entered: Liver and Spleen.
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| Chemical constituents |
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The main effective ingredients of jiang huang are curcumin, demethoxycurcumin and bisdemethoxycurcumin. Another effective ingredient is volatie oil, which contains turmerone, zingiberene, phellandrene, cineole, sabinene and borneo, etc..
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| Pharmacological actions |
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| Effects on cardiovascular system |
10 minutes' perfusion of water extract-alcohol precipitation of jiang hua to isolated rat hearts could lower the blood flow volume of coronary vessles by 16.3%, and decrease the heart rate. Ethanol extract of jiang huang could lower the blood pressure in anaesthetized dogs. |
| Influence over blood rheology |
Ethanol extract of jiang huang could lower the whole blood and plasma ratio viscosity, platelet adnesivenss and inhibit the thrombosis in vitro. Curcuin could inhibit the platelet aggregation. |
| Effects on the uterus |
jiang huang decoction and infusion had excitatory effect on isolated uteruses of mice and guinea pigs. Intraperieoneal or hypodermic injectionof water decoction of pian jiang huang could terminate the prennancy in early, middle and late stage. |
| Blood fat lowering effect |
Ethanol extract, volatile oil of jiang huang and curcumin could significantly lower the plasma TC and TG in rats with experimental hyperlipemia. jiang huang preparations could also significantly lower the serum cholesterol and b-lipoprotein in rabbits with experimental hyperlipemia. |
| Anti-tumor effect |
Topical administation of curcumin could inhibit skin cancer induced by TPA in mice. Intraperitoneal injection of curcumin could inhibit the tumor formation, and increase the survival rate of mice injected with Dalton lymphoma. |
| Others |
jiang huang decoction could increase the bile secretions. Volatile oil of jiang huang had good anti-bacteiral effect on staphylococcus aureus. Water infusion of jiang huang had inhibitory effect on various dermatomyces. Ethonal and water extract of jiang huang hand anti-inflammatory effect. jiang huang powder could increase the mucine content in gastric juice, and protect the gastric mucous membrane from stimulation. |
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| Clinical Studies |
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| Hyperlipemia |
E Huang Jiang Zhi Tablet (jiang huang 30g, e zhu 30g, huang jing 20g, yu zhu 20g, da haung 20g, shan zha 20g, shi chang pu 15g, chai hu 15g), 4~5 tablets (containing 1~1.2g crude drug), tid. 30 days as a course of treament. The method was used to treat 124 cases of hyperlipemia, and 87 markedly effective, 22 effective, 15 ineffective. |
| Stye and otitis media |
jiang huang powder, camphor and menthol were made into ointment. 55 cases of stye and otitis media were treated, and 50 cases were cured after 2 days (2 times of external application). |
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| References |
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Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998 |
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