San Leng - Sparganium stoloniferum

Professional Data
 Pin Yin
San Leng
 
 Latin
Rhizoma Sparganii
 Introduction Back to Top
Rhizoma Sparganii is the dried rhizome of Sparganium stoloniferum Buch.Ham. (Fam. Sparganiaceae). The drug is collected from winter to the next spring, washed clean, peeled, and dried in the sun.

 Western medical Back to Top
sang leng is used to treat urinary system stones, infertility due to endometriosis, swelling of tonsils and tumors, etc..

 Eastern medical Back to Top
  • Pattern: Breaks Blood, removes stagnant Blood, moves qi and dissolves stagnant food.
  • Properties: Pungent, bitter, neutral.
  • Channels entered: Liver and Spleen.
 Chemical constituents Back to Top
sang leng contains volatile oil and starch.

 Pharmacological actions Back to Top
Miscellaneous effects

Water decoction-alcohol extract of san leng could lower plasma vixcosity, whole blood viscosity under high shear, improve the erythrocyte deformability, increase RBC electrophoresis rate, inhibit platelet aggregation and lower fibrinogen. 10 minutes perfusion to isolated rat heart could lower the blood flow volume in coronary vessels. san leng decoction could inhibit the in vitro thrombosis. san leng decoction could inhibit the in vitro thrombosis. It could also dilate blood vessles and increase the phagocytic functions.

san leng oculd could lower serum T4, and lower plasma camp in mice.

Anti-tumor effects

san leng had inhibitory effect on cancer cells. 30% San Leng E Zhu Injection had significant inhibitory effect on S180 in mice.

Effect of Rhizoma Curcumate Zedoariae and Rhizoma Sparganii on apoptosis of human lung cancer cell line A549

The object was to study the medhanism of inhibitory and tumor killing effects of two kinds of Chinese traditional herbs, rhizoma Curcumate zeloariae and Rhizoma Sparganii. Lung cancer cell line A549 was adopted as target cell. The research examined tumor cell apoptosis induced by the herbs with flow cytometry when the target cell was cultured with the herb substration for 24h. The substraction both two kinds of herbs can induce tumor cell apoptosis. The great synergic effect to induce target cell apoptosis was also found out. The results suggested that to induce target cells apoptosis is the man mechanism in inhibiting and killing tumor by ther herbs.

--Wang Z, Zhang JF, Fu GF. Journal of Capital University of Medical Sciences. 2001; 22(4): 304~5.

 Clinical Studies Back to Top
Urinary system stones

Hua Yu Niao Shi Tang (sang leng, e zhu, chi shao, che qian zi, 15g each; chuan shan jia, zao jiao ci, tao ren, chuan niu xi, qing pi, bai zhi, zhi ke, 9g each; ru xiang, mo yao, sheng yi yi ren, 6g each; jin qian cao 30g) were used to treat 45 cases of urinary system stones, and the total effective rate was 92.3%.

Infertility due to endometriosis

Formula used in non-menstural period: sang leng, e zhu, chuan lian zi, chi shao, gui zhi, fu ling, tao ren, dan pi, 10g each; yan hu suo, dan shen, zao jiao ci, 12g each; xia ku cao 15g. The formula was combined with the formula containing wu ling zhi which was used in menstrual period to treat 35 cases of infertility due to endometriosis, and 14 cases got pregnant.

Refractory swelling of the tonsils

Po Xue Xiao E Tang (experimential formula): san leng, e zhu, zhe chong, jie geng, tu bei mu, sheng gan cao, 10g each; dan shen, xuan shen, 30g each; tian hua fen 30g. Modify the formula according to accompanied symptoms, 1 dose daily, 15 days as a course of treatment. After 1~3 courses, 31 out of treated 41 cases were cured and 10 improved.

Tumors in late stage

Po Shi Mixture (experimential formula): chuan po shi 100g, san leng 50g, ma bian cao 50g. 31 cases of malignant tumors in late stage were treated with above formula and 24 cases were effective.

 
 References Back to Top

Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998