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Shi Hu - Dendrobium loddigesii
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Professional Data |
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 Pin Yin
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Shi Hu
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| Latin
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Herba Dendrobii
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| Introduction |
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Herba Dendrobii is the fresh or dried stem of Dendrobium loddigesii Rolfe., Dendrobium fimbriatum Hook. var. oculatum Hook. , Dendrobium chrysanthum Wall. , Dendrobium candidum Wall. ex Lindl. or Dendrobium nobile Lindl. (Fam. Orchidaceae). The drug is collected in all year round. For the fresh material, removed from root and soil, and for the dry material, removed from foreign matter, treated with boiling water for a moment or baked gently to soften, then rubbed while baking or sun drying to remove the leaf sheaths, and dried. Some rootlets of Dendrobium candidum are trimmed off, stir-fried while twisting to a spiral or spring form, then baked to dryness and known as Erhuanshihu (earring-like Dendrobium).
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| Western medical |
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This herb is often used to treat gastritis, burred vision, cough, hepatitis, diabetes and emaciation, etc..
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| Eastern medical |
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- Pattern: Nourishes yin, clears Heat, benefits the Stomach, generates body onload="highlight();" Fluid, brightens eyes.
- Properties: Sweet, slightly cold.
- Channels entered: Stomach and Kidney.
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| Chemical constituents |
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shi hu contains alkaloids including dendrobine, nobilonine and dendramine, and starch, etc..
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| Pharmacological actions |
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| Effects on digestive system |
Oral administration of shi hu decoction could help digestion by promoting the secretions of gastric juice, relax the bowels by exciting the peristalsis. But in large dosage, it could anaesthetize the intestinal muscles. |
| Anti-febrile and analgesic effect |
Dendrobine had certain analgesic and anti-febrile effect. |
| Effects on the cardiovascular system |
shi hu fluid extract had inhibitory effect on isolated toad's heart. At large dosage, dendrobine could inhibit respiration and the heart, lower the blood pressure. At toxic dosage, it could induce convulsion. |
| Influence over immune system |
shi hu decoction could improve the phagocytosisof mice macrophages. And its polysaccharide could elevate the E-RFC formation rate of peripheral lymphocytes in patients with cancer, the elevated value was similar to thymosin. |
| Anti-tumor effect |
In vitro and in vivo antitumoral phenanthrenes from the aerial parts of Dendrobium nobile. |
Two phenanthrenes were isolated from the aerial part of Dendrobium nobile Lindl. and their structures were identified to be 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene (1) and denbinobin (2), among which the former has been first isolated from this plant. These two compounds were found to be cytotoxic against A549 (human lung carcinoma), SK-OV-3 (human ovary adenocarcinoma), and HL-60 (human promyelocytic leukemia) cell lines. Compound 1 also showed antitumor activity on the life span of ICR mice intraperitoneally implanted with 1 x 10(6) cells of sarcoma 180. |
--Lee YH, Park JD, Baek NI, Kim SI, Ahn BZ. Planta Med. 1995 Apr;61(2):178-80.
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| Clinical Studies |
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| High fever |
shi hu (fresh) 30g, water decoction. |
| Achlorhydria |
shi hu, xuan shen, 15g each; bai shao 9g each; mai dong, nuo dao gen, 12g each. Water decoction. |
| Emaciation |
shi hu, mai dong, niu xi, du zhong, dang shen, gou qi, bai shao, 9g each; zhi gan cao, wu wei zi, 6g each. Water deocction. |
| Pre-cancer lesion of the stomach |
dang shen, shi hu, xu chang qing, e zhu, gu ya, mai ya, 15g each; bai hua she she cao, teng jing gen, pu gong ying, 30g each; fu ling, bai shao, lian qiao, 12g each; bai zhu, ban xia, fo shou, zhi ke, 10g each; tao ren 9g; sheng gan cao, hong hua, chen pi, gan song, 6g each; chuan huang lian 3g; wu zhu yu 3g. Modify the formula according to TCM patterns, 1 dose daily, water decoction, for 3~6 months. Among 30 treated cases, 28 were effective. 22 cases were proved effective through pathological examination. |
| Hepatitis B |
nan sha shen, huang jing, shi hu, chi shao, bai shao, hu zhang, 15g each; gou qi, dan pi, mai dong, 12g each; sheng shan zha 30g. Modify the formula according to TCM differentiation. Water decoction, 1 dose daily. 48 out of 60 treated cases were effective. |
| Diabetes |
For diabetes of qi and yin deficiency: huang qi, dan shen, huai shan yao, 24g each; shi hu, sha shen, fu ling, 12g each; gao li shen 8g, ku shen 18g; huang jing, wu wei zi, suan zao ren, long yan rou, 10g each. |
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| References |
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Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998 |
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