Zao Jiao - Gleditsia sinensis

Professional Data
 Pin Yin
Zao Jiao
Fructus Gleditschiae chinensis
 Introduction Back to Top
Fructus Gleditschiae chinensis is the ripe fruit of Gleditsia sinensis Lam. (Fam. Leguminosae). The drug is collected in autumn, dried, and cut into slices.

 Western medical Back to Top
The herb is indicated in the treatment of primary epilepsy and senile chronic bronchitis.

 Eastern medical Back to Top
  • Pattern: Dispels Wind Phlegm, opens orifices, dispels Phlegm, stops cough, reduces swelling, dissolves lump.
  • Properties: Acrid, warm, mildly toxic.
  • Channels entered: Lung and Heart.
 Chemical constituents Back to Top
The herb mainly contains triterpenoid saponin, tannic acid, cerylalcohol, stigmasterol and sitosterol, etc..

 Pharmacological actions Back to Top
Expectorant effect

zao jiao could stimulate gastric mucus and reflectively promote the mucus secretions in respiratory tract and exert its expectorant effect.

Anti-bacterial and anti fungi effect

zao jao could inhibit bacillus coli, shigella dysenteriae, and comma bacillus, etc.. It also had inhibitory effect on seom dermal fungi.


Saponins contained in zao jiao had strong hemolysis effect.

 Clinical Studies Back to Top
Primary epilepsy

Dian Xian Wan: zao jiao 100g, zhi nan xing 60g, ban xia 60g, bai jie zi 50g, shi chang pu 25g, sheng long gu 10g, sheng mu li 10g, hu po 15g, quan xie 25g, ci shi 10g, chai hu 50g, zhu sha 15g, yu jin 100g, tan xiang 50g, zhi ke 50g, wu gong 10g, chuan lian 40g, ban jiang can 45g, di ling 30g, da huang 20g, huang qin 30g. All drugs were grounded into fine powder and made into honeyed pill, 5g each pill, three pills every day. Above drugs were one course. After 1~2 courses, among 54 treated primary epilepsy, 30 cases were clinically cured, 21 effective, and 3 ineffective.

Senile chronic bronchitis

Dan Jia Pian (pig bladder, zao jiao, cao he che) was used treated senile chronic bronchitis, 108 cases of senile chronic bronchitis were treated, and 84.26% cases were effective after the first course.

 References Back to Top

Except those noted, all references come from Weng Weiliang, et al., Clinical Chinese materia medica, Henan Science & Technology Press, 1998